Nursing Acceleration Challenge Exam (NACE) PN-RN Practice Test

Patients undergoing repeated transfusions are at increased risk for which condition?

1. Deep vein thrombosis

2. Hemorrhage

3. Electrolyte imbalance

4. Hemochromatosis

The correct answer is: Hemochromatosis

Patients undergoing repeated transfusions are at increased risk for hemochromatosis due to the accumulation of iron in the body. Each unit of red blood cells contains a significant amount of iron, and when blood is transfused, the iron load increases. The human body has no active mechanism to excrete excess iron; instead, it gradually accumulates in various organs, such as the liver, heart, and pancreas. Over time, this accumulation can lead to tissue damage and functional impairments, resulting in conditions associated with iron overload, collectively referred to as hemochromatosis. In contrast, while patients may face issues related to deep vein thrombosis, hemorrhage, or electrolyte imbalances, these conditions are not specifically tied to the consequences of multiple blood transfusions in the same manner as hemochromatosis. This makes hemochromatosis the most relevant condition associated with repeated transfusions.